Adequate SIRT activity dose is as important as adequate chemotherapy dose – Authors' reply

Is Hesaabdaaree an Adequate Equivalent for Accounting?

Some of the difficulties and misunderstandings that happen in accounting theory, practice, regulation and education are grounded in language and linguistics. As an illustration of this the Persian equivalent of 'accounting' is linguistically analysed to reveal how a mistranslation may cause difficulties in understanding and improving Iranian Accounting. This paper shows how Hesaabdaaree is not ...

Adequate as the Forthcoming “ Mindscience ” ?

The widespread use of brain imaging techniques encourages conceiving of neuroscience as the forthcoming “mindscience.” Perhaps surprisingly for many, this conclusion is still largely unwarranted. The present paper surveys various shortcomings of neuroscience as a putative “mindscience.” The analysis shows that the scope of mind (both cognitive and phenomenal) falls outside that of neuroscience....

Searching for an adequate dose : Combining Multiple Comparisons and Modeling

The search for an adequate dose involves some of the most complex series of decisions to be made in developing a clinically viable product. Typically decisions based on such dose-finding studies reside in two domains: the first being one of “proof” that the treatment provides evidence of effectiveness. The second concerns the need to choose dose(s) for further development. The analysis of dose ...

What is adequate?

GnRH Stimulation Test in Precocious Puberty: Single Sample is Adequate for Diagnosis and Dose Adjustment

OBJECTIVE Gonadotropin stimulation test is the gold standard to document precocious puberty. However, the test is costly, time-consuming and uncomfortable. The aim of this study was to simplify the intravenous gonadotropin-releasing hormone (GnRH) stimulation test in the diagnosis of precocious puberty and in the assessment of pubertal suppression. METHODS Data pertaining to 584 GnRH stimulat...